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Groundbreaking Knowledge & Tools
 

MESICS Stress and Longevity References

The following research articles and studies provide information about the nutritional and clinical foundation for regularly using the MESICS Stress and Longevity Formula™

 
Abbey M. The importance of vitamin E in reducing cardiovascular risk. Nutr Rev 1995;53 Suppl.S28-S32.
Albert, C., et al. 1998. Fish consumption and risk of sudden cardiac death [see comments]. JAMA, 2, 279–238.
Arita, Makoto, et al, Stereochemical assignment, antiinflammatory properties, and receptor for the omega-3 lipid mediator resolvin E1 Journal of Experimental Medicine March 2005;201(5):713-722
Ageing Research Reviews, Stress, Neuropeptides and Age-Related Diseases Volume 4, Issue 2 May 2005, Pages 141-194
Anderson LE, Sr., Myer RO, Brendemuhl JH, McDowell LR. Bioavailability of various vitamin E compounds. J Anim Sci 1995;73:490-495.
 
Bartter FC, Berkson BM, Gallelli J and Hiranaka P. “Treatment of Four Delayed-Mushroom-Poisoning Patients with Thioctic Acid (Alpha Lipoic Acid).” in Amanita Toxins and Poisonings, eds Faulstich, H., Kommerell, B., and T.Wieland, Verlag Gerhard Witzstrock, Baden-Baden, New York 1980.
Berkson BM. “A Conservative Triple Antioxidant Approach to the Treatment of Hepatitis C. Combination of Alpha-Lipoic Acid (Thioctic Acid), Silymarin and Selenium. Three Case Histories.” Medizinische Klinik 94(3), 1999: 84-89.
Boldyrev A, Song R, Lawrence D, et al. Carnosine protects against excitotoxic cell death independently of effects on reactive oxygen species. Neuroscience. 1999; 94(2):571-7.
Bougnoux, P., et al. 1999. Cytotoxic drugs’ efficacy correlates with adipose tissue docosahexaenoic acid level in locally advanced breast carcinoma. Br. J. Cancer, 79, 1765–1769.
 
Campbell JD, Cole M, Bunditrutavorn B, et al. Ascorbic acid is a potent inhibitor of various forms of T cell apoptosis. Cell Immunol 1999;194:1-5.
Chin J., & Dart, A. 1995. How do fish oils affect vascular function? Clin. Exp. Pharmacol. Physiol. 22, 71–81.
 
de la Fuente M, Ferrandez MD, Burgos MS, et al. Immune function in aged women is improved by ingestion of vitamins C and E. Can J Physiol Pharmacol 1998;76:373-80.
Dietary supplementation with n-3 polyunsaturated fatty acids and vitamin E after myocardial infarction: results of the GISSI-Prevenzione trial. Gruppo Italiano per lo Studio della Sopravvivenza nell'Infarto miocardico. Lancet 1999 Aug 7;354(9177):447-55.
Duffy SJ, Gokce N, Holbrook M, et al. Treatment of hypertension with ascorbic acid. Lancet. 1999;354(9195):2048-2049.
 
Epel, Elissa Ph.D., et al, Accelerated telomere shortening in response to life stress. Proc Natl Acad Sci U S A. 2004 Dec 7;101(49):17312-5. Epub 2004 Dec 1.
 
Fairfield KM, Fletcher, RH. Vitamins for chronic disease prevention in adults; clinical applications. JAMA 2002 June 19:287 (23): 3127-9.
 
Giovannucci E, Stampfer MJ, Colditz GA, et al. Multivitamin use, folate, and colon cancer in women in the Nurses' Health Study [see comments]. Ann Intern Med 1998;129:517-24.
Gokce N, Keaney JF, Jr., Frei B, et al. Long-term ascorbic acid administration reverses endothelial vasomotor dysfunction in patients with coronary artery disease. Circulation. 1999;99(25):3234-3240.
Green, Kim, et al, (Omega-3 fatty acid may help prevent Alzheimer's brain lesions) Dietary Docosahexaenoic Acid and Docosapentaenoic Acid Ameliorate Amyloid and Tau Pathology via a Mechanism Involving Presenilin 1 Levels. Journal of Neuroscience, April 18, 2007 • 27(16)
Gulyaeva NV. Superoxide-scavenging activity of carnosine in the presence of copper and zinc ions. Biochemistry (Moscow). 1987; 52(7 Part 2):1051-4.
 
Harris WS, Isley WL., Clinical trial evidence for the cardioprotective effects of omega-3 fatty acids. Curr Atheroscler Rep. 2001 Mar;3(2):174-9.
Henriksen EJ (2006). "Exercise training and the antioxidant alpha-lipoic acid in the treatment of insulin resistance and type 2 diabetes". Free Radic Biol Med 40 (1): 3-12. PMID.
Hughes DA. Effects of dietary antioxidants on the immune function of middle-aged adults. Proc Nutr Soc 1999;58:79-84.
Hugo, Fernando N., Chronic Stress, Depression, and Cortisol Levels as Risk Indicators of Elevated Plaque and Gingivitis Levels in Individuals Aged 50 Years and Older. Journal of Periodontology 2006, Vol. 77, No. 6, Pages 1008-1014
Hung HC, Joshipura KJ, et al, Fruit and vegetable intake and risk of major chronic disease. J Natl Cancer Inst 2004 November 3;96(21):1577-84.
 
Kantha S.S, et al, Carnosine Sustains the Retention of Cell Morphology in Continuous Fibroblast Culture Subjected to Nutritional Insult Biochemical and Biophysical Research Communications, Volume 223, Number 2, June 1996 , pp. 278-282(5)
Koroshetz WJ, Jenkins BG, Rosen BR, Beal MF. Energy metabolism defects in Huntington's disease and effects of coenzyme Q10. Ann Neurol 1997;41:160-5.
 
Langsjoen PH, Langsjoen A, Willis R, Folkers K. Treatment of hypertrophic cardiomyopathy with coenzyme Q10. Mol Aspects Med 1997;18:S145-51.
Losonczy KG, Harris TB, Havlik RJ. Vitamin E and vitamin C supplement use and risk of all-cause and coronary heart disease mortality in older persons: the Established Populations for Epidemiologic Studies of the Elderly. Am J Clin Nutr. 1996;64(2):190-196.
 
McFarland GA, Holliday R. Further evidence for the rejuvenating effects of the dipeptide L-carnosine on cultured human diploid fibroblasts. Exp Gerontol. 1999; 34(1):35-45.
 
Neuringer M, Anderson GJ, Conner WE. The essentiality of n-3 fatty acids for the development and function of the retina and brain. Ann Rev Nutr. 1988;8:517-541.
NIOSH Publication No. 99-101: JOB STRESS.
 
Osganian SK, Stampfer MJ, Rimm E, et al. Vitamin C and risk of coronary heart disease in women. J Am Coll Cardiol. 2003;42(2):246-252.
 
Packer L, Witt EH, and Tritschler HJ (1995). "alpha-Lipoic acid as a biological antioxidant". Free Radic Biol Med 19: 227-250.
Pagani, Massimo, M.D., Even mild stress can raise blood pressure. Hypertension 2002;139:184-188.
Peruzzo, Diane C, et al, A Systematic Review of Stress and Psychological Factors as Possible Risk Factors for Periodontal Disease Journal of Periodontology 2007, Vol. 78, No. 8, Pages 1491-1504
Preedy VR, Patel VB, Reilly ME, Richardson PJ, Falkous G, Mantle D. Oxidants, antioxidants and alcohol: implications for skeletal and cardiac muscle. Front Biosci. 1999 Aug 1;4:e58-66
 
Roberts PR, Zaloga GP. Cardiovascular effects of carnosine. Biochemistry (Mosc). 2000 Jul;65(7):856-61.
Romieu, Isabelle, Et al, Omega-3 Fatty Acid Prevents Heart Rate Variability Reductions Associated with Particulate Matter. American Journal of Respiratory and Critical Care Medicine Vol 172. pp. 1534-1540, (2005)
Ruffman R and Wendel A: GSH rescue by N-acetylcysteine. Klin. Wochenschr. 1991; 69:857-862.
 
Sapolsky, Robert, M., Ph.D., Organismal stress and telomeric aging: An unexpected connection, Proceedings of the National Academy of Sciences, December 14, 2004, vol. 101, no. 50, 17323-17324
Schnied-Kofman N and E Sheiner. Does stress effect male sterility. Medical Science Monitor. 2005. 11(8): SR11-13.
Smilkstein MJ, Knapp GL, Kulig KW, and Rumack BH: Efficacy of oral N-acetylcysteine in the treatment of acetaminophen overdose. N Engl J Med 1988; 319:1557-1562.
Schulz P, Kurschbaum C, Prubner J, Hellhammer D. Increased free cortisol secretion after awakening in chronically stressed individuals due to work overload. Stress Medicine 1998; 14:91-97.
Stadtman ER. Protein oxidation and aging. Science. 1992; 257(5074):1220-4.
Steinmetz KA, Potter JD. Vegetables, fruit, and cancer prevention: a review. J Am Diet Assoc. 1996;96(10):1027-1039.
Strohle A. The neuroendocrinology of stress and the pathophysiology and therapy of depression and anxiety Max-Planck-Institut fur Psychiatrie,Munchen.USA Nervenarzt 2003 Mar;74(3):279-92
Stvolinsky SL, Kukley ML, Dobrota D, et al. Carnosine: an endogenous neuroprotector in the ischemic brain. Cell Mol Neurobiol. 1999; 19(1):45-56.
 
Tafet, Gustavo E, and Smolovich, Jaime, Psychoneuroendocrinological Studies on Chronic Stress and Depression Annals of the New York Academy of Sciences 2004; 1032 (1), 276–278.
Travis J (1993) New piece in Alzheimer’s puzzle. Science 261:828–829.
 
Van Schooten, Frederik Jan, Effects of Oral Administration of N-Acetyl-L-cysteine. Cancer Epidemiology Biomarkers & Prevention Vol. 11, 167-175, February 2002
 
Wiznitzer A, Ayalon N, Hershkovitz R, Khamaisi M, Reece EA, Trischler H, Bashan N. Lipoic acid prevention of neural tube defects in offspring of rats with streptozocin-induced diabetes. Am J Obstet Gynecol 1999;180:188-93.
 
Zhang S, Hunter DJ, Forman MR, et al. Dietary carotenoids and vitamins A, C, and E and risk of breast cancer. J Natl Cancer Inst. 1999;91(6):547-556.
Ziegler D, Hanefeld M, et al. Treatment of symptomatic diabetic polyneuropathy with the antioxidant alpha-lipoic acid: a 7-month multicenter randomized controlled trial (ALADIN III Study). ALADIN III Study Group. Alpha-Lipoic Acid in Diabetic Neuropathy [In Process Citation]. Diabetes Care 1999;22:1296-301.

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DISCLAIMER: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

1 After a comprehensive review by nutritional scientists, the MESICS Ultra Prevention multivitamin mineral formula was ranked the Number One multivitamin available exclusively to the professional health care market. And like the core MSLF, the MESICS Ultra Prevention formula has independently won the NutriSearch GOLD Medal of Achievement award. The Gold Medal Award means that the MESICS Ultra Prevention Multivitamin-mineral™ meets the most stringent manufacturing standards. Standards that are your guarantee of exceptional quality and safety and ingredient identity, potency and purity.

2 Which means they’re in accord with one of the worlds highest and most recognized standards of excellence—the International Organization for Standardization’s (ISO) approval and recognition. The MSLF meets exceptional pharmaceutical standards including a full 3rd party laboratory analysis of active ingredients. To ensure highest levels of identity, potency, purity, absorption and bioavailability.

 

Within 30 days of taking the MESICS SL Formula, you’ll experience the difference.

  • You’ll feel more sharp, more focused and more alert
  • You’ll feel stronger and more resilient—stress won’t knock you down
  • You’ll feel more energy—good quality energy—throughout your day

 

Your RESULTS:

  • You’ll feel, look and perform better
  • You’ll be more self-confident and self-assured
  • You’ll have fewer negative states of mind: anxiety, worry, depression
  • You’ll have more heart and immune system support
  • You’ll age better
  • You’ll “crash” less and if you do—you’ll bounce back sooner

Our PROMISE—if within 30 days, you’re not totally thrilled with your results, then just let us know. We’ll refund 110% of your product purchase. No questions asked.

You have nothing to lose and so you can buy now in total confidence.

 
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*M-E-S-I-C-S is an acronym for a Latin phrase: Mens Sana In Corpore Sano. Which means "A Sound Mind in a Healthy Body". The ultimate standard for health, well-being and quality of life.

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